Our new Very clear+ tissue clearing procedure is the only real technique that delipidates samples without transform in morphology and with negligible impact on structural integrity.
Megatome is actually a vibrating microtome intended to part a wide number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue injury and data reduction.
Antibodies could get weeks to diffuse by means of just a few millimeters of tissue, using a steep labeling gradient from surface area to core.
Megatome is made for precision: the blade vibrates at the next frequency and bigger amplitude array than other microtomes, and contains a exceptional deflection Regulate system.
SE uses a rotational electric powered industry to disperse remarkably electromobile molecules (for instance antibodies or surfactant micelles) during a porous sample with no harmful electrically charged structures throughout the tissue. This permits 2-4 day clearing of intact organs,
Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them totally transparent. This allows gentle penetration to the sample and guarantees the acquisition of higher-resolution, in-aim impression knowledge.
Megatome is a novel microtome that enables for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with negligible tissue hurt and information decline.
eFLASH is actually a immediate tissue labeling strategy that allows for uniform total-organ staining in 20 rounds of labeling.
The SmartSPIM gentle sheet microscope offers unparalleled resolution and acquisition speed all through intact tissue volumes, while its modular layout enables you to up grade and customize particular person components.
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Leverage the Very clear+ tissue clearing system, coupled with eFLASH and patented stochastic electrotransport technologies, to swiftly obvious and label full organs. Key highlights and attributes incorporate:
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